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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '228d8cf7d08ea059bcdf36381c4e5791f6442e8aede48676db23ea4039859f7f' 
  AND token = 'bPQtL6uJq7RsPpNRsch5v3NmPN07H66Dp9BkXJDsR24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}