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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '461dbc8ad2aaa09f82b85499118172d7e1e0e7b43215b76f6df8f23f3e008310' 
  AND token = '3zA5W0P/aMjIfgct9ck+hryQxhSdRIIgj167xDkd7Xs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}