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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3181ed55be0c385c6b3131580a52db7f689e0b1974f3317b708f6d04b4374da2' 
  AND token = 'U7tvTHqK41+EQZ57oym/74k9MZeh8oooggYVPel4uEU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}