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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2caf6acf343f644dc116fa243a7c957c6708a6b34aeffa4de89b50b0b087d0fd' 
  AND token = 'DEsKnLxHDyJ50mQUm+D5uc+ifIyMDPKX+MqTmB2hiwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}