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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81d9025269fa475e192c6605e68cc06592c104f0989768f9aed767a3faa0cb8f' 
  AND token = 'hPeFHjY9LbkHI3wwM/FYfK3P6D5mQ78u+Xv3EeUS2e8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}