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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26cf64e5ee5fc8cca80e2591901f204257fc03d8434004a423fa491f7ac0878a' 
  AND token = '4AqzbQwdSv8ddBOa4YvRS+Fb2wpCfQZ4BXA3up9Qf0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}