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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f21890bd9eae61dccf3e64761d3838cfa668f10666c49041dfddf0f474183bb' 
  AND token = 'Ok0JBpOjAMjHfoMmHLu+p4Eu5cTDiLUUmuZ4olsS0/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}