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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c53d313ec5877833cead08df09f1a46e8337a31dbfe5b474ba79d5fb0378a7ea' 
  AND token = 'pzI0URg4DX1en5pd8xaBv8NA+Zjj3TdKMiCDTqEMuuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}