SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a2df2e61d706eed26d227979600fab04d6a3f8299a9e245ab94abdaf3ccb160' 
  AND token = 'jBeaWpVgBq5KKJx9y6IthRhmMKUpE1CxenSBWGZ5zrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}