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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a165c19ef719940eb9a4b433580cec1a6d7fc3847766cdc407b0ec0280b48898' 
  AND token = 'lDFmlwzI2VmEGbcdTSMiDU1GN9aVdDwqrBWjG6xFV/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}