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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7f4b3e02f9115afd69f6a17af46311ca3427b51070ee5f75bebe50d93e2b263' 
  AND token = '5UT9OG8n8FzbyDlpf2VGQ9ZYb+UNiYW97ecjjtrJmc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}