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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21d5dc067a664dfcfb8279dbb5518537117bb562024fa8126d80e8e1e826188f' 
  AND token = '3cirXRmjp5GB5AB8aSSHi+MxzCvy5W4RZ/p3tf/fXSM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}