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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0d8f6534103e298bb46be436f1039e2187ac09ef993a454130e30cc7db0469f' 
  AND token = '7p5jFA/QmMFiFv6+XxlWQQBtxeuTd657KS7R4xlGlAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}