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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16203bad7bbd7b5e2bb846b799326fc2fc5ead412374e2ba1ab7a0849f320495' 
  AND token = 'jmCatraGnu01EzxlNtk/Oc0v7ejOG3rtozeMdCfHvBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}