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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '727f0b8ab7d7cd7225c39381523cfddf0db3cbb08ca125212d3d1a69900df54a' 
  AND token = 'sQhCfA7Q1wbPAFZsyPp12S2Gf+HdP0zCO6cBKI1fs6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}