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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0b2bffffee5a1f0ed30f3e05e3e3e16d255006c56de4d29c2fed027d1d03b52' 
  AND token = '2+BLfExFjFFfq6RapvmpbJckBMcI7PDqjPMexRHvP/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}