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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '221ebaec8f2c7d3bdb60238f14d9bb266f8c60cbad22cc32e9df9d329bffe84a' 
  AND token = 'TZn9N0rEmQ3l9eKGSOzMHssghhoJlw1P0y35m53Kzd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}