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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ae1245f91b3077801b52ac330b05ee2866cd96dd49b4032eb98a4f70cad9349' 
  AND token = '5jkOknidHrMityqI5wymjGtILhApdTStHUzjwkvnKVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}