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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4132be49a0eaf5dbc31c814ac60137080feb6fc157d86e1fba80e634f57ea727' 
  AND token = 'NdDu0EOvm9XgheEEEzjrUYtJHQYLC5xnrjdex15rABU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}