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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5b63b98cd37aa5ad1c46155bba1aa0f1375dd21c24de93e334b6c355e9e86af' 
  AND token = 'cHGmg+LaVBuRGWs3Pwhtt7VrwcqwDcRULrWkZmcj4eY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}