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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '280a6109606fd1089afa12c9dc8950aa38234c0dbd0d0fe859b0be1615b2c1eb' 
  AND token = 'gAxlkS1NH9/OR1zaVw/J4G6z9NNmcQaMWFjzrj5H4Uk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}