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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5b1c011d11bd51a01c06c44e726b446259c8dbf25a899751394418c049cc218' 
  AND token = '8HLYuBOXyT39/gpo+q1j/7f+E+DxyZbjnUscpg6y9yc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}