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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72ea46f44fd3827e8d82282528509ad4ec17ffb8305c17aea1afa5a98b3570f8' 
  AND token = 'qloxg997kJzEmxJH+sDJixX8SUSC6ME1P4uXaNf1czE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}