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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e16e2d11b030d00b24388ad3da0c6c1968e1e39982744a019018a8e781dfd72c' 
  AND token = '2Wz1DQMt1iX5T20PH72AhGkdyZ1wCTkaYzb6oXj6bt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}