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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fb9e18023434f77004831cda878543d28aa3fe85cda4b15c7f59d403a7bfbf8' 
  AND token = 'LkGErxaLYRqZtpe+gtb+S+9tg1UFjr7YBGgwnSQUsPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}