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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3ea45cf7f531b03fedaa2eb018145c2e4f5bba61cb2156f8a06fefaf7df6207' 
  AND token = '6ftOtu5+zGcykiC2gpk+R0RL/vljtNyy80330JtedR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}