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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b2e5f2b7a66eb52ed9b268fe726ae997d3215a9045a2a27538fbfcbab0ec073' 
  AND token = 'fQbKBVYl2RpWYsVmo+b/yB9b1UuNumZHGC6RCb/i79Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}