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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '601debb12be96208bb78b294c5937c9351b60623466a52a99a1c9ee2b6a2925b' 
  AND token = 'JiUfqHylVHYz1IN5AQzmanVmQfnK0pWdk6MCXivmwk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}