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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd245a3fb1a08b8f22e8ee74307b65ff51b5720c76d40982b8ed815c26920146' 
  AND token = 'jkW5jyFbl3clMI8p+mZR8T1UJiXPUe1pHbyzccniqD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}