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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19c246dd36b300000febf34142ec2ea11ca7402f7339acb55ba21363d5f44329' 
  AND token = 'N9pjEprlQioguwKMStRzl2sBfjwjgQXtIied/kJENCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}