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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e03d012cfdee498f04caf48d6789c51702323990f8fba4d5ffd376d9b3e02bb' 
  AND token = '40DNtjZOC0NSjL1HdsAaFbAkwXJaC/W3ANkdC6vPuQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}