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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac8aa7e751d841e5f05745478a1611a427f9d909e8bd5999d77999775c5fec98' 
  AND token = 'WMvVKIM5SuDE4tbc0y1bAW5h695ueR+qF/tSxj4ZOAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}