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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8493390288f7cc138df22f839c1f8dfb02a3042c733acb45438653a38f1f5773' 
  AND token = 'MJ9C0zh+kCsgym5DcS+TZEZPuvyJKS3QxPhRF4B36Q0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}