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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d759423c12e196d823bf9b44fc3c005d0d3b2333f01835e17be0d37719e4e77' 
  AND token = 'ek4xD8qRnkIl2lUpK3rXtuo2/zRH4AONv2bKTAh+3vw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}