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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff217ee196d80a074cd0fc135baf1bde4bc4f4327094a361e95aab265b266b48' 
  AND token = '+4Vw3dkXmkvZa8XBnn9U3SLsB4CJ94nyiQi0PWm8KSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}