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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f0c70c18fc6b50a571a414a5cf9bf61494dae1b0030e6d17cbc64b74c0fee9f' 
  AND token = 'wpEJ2eOaWWPrc4gKVVPSrNqXvx0taUqqp0ECqN8xyjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}