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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25e57b721dbb60950902085c6958c78a73d8a2f163b62f5a5cefc80e8400067d' 
  AND token = '/EPK4k6N0nrMgoiKynhdYlKASadQ9rfkL0pNRm261Ds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}