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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cb81c866148e65ebff7b5cb849f34266501741e6ec807ceb9060f2e87ec3bac' 
  AND token = '0jSZ5uFodKAitGf/pmySJtt+/EzRRG8+iQnRQ1cH5ZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}