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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a596a4583e8264af67705c75e270cde05c9297443b6fe831b55ec3742e85d03f' 
  AND token = 'kL64eqPtuqh1AezUgk60Fvs5A8GUkSm5VtHj0uuzg4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}