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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b8ca9f0ac5967badef2d2678a77697c7af44a223fc87f345a7828f82344a8aa' 
  AND token = '/Qq/u6DjnQa11DfaV3UfYV9b2SWfsSUR5zYXpnZBbrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}