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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75bde2c9702a5e17e73448695a69c1b0f212ddc887eaf64e67eed900e616480d' 
  AND token = 'PMKALwRAUctqOId0ms+rdjMIU0IS7+xu12AO/uv/6mY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}