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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21e9f4b8be5dc88ca9c904bfdaea60402a357b93172273591b1ef7a64fe1c912' 
  AND token = 'SGG4KVXB3dRtgAxe8Op8rVhs4FpPcNQc1Th6wmZZqAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}