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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f300dbcc0d1e881be2db380e9107dc236243939493dddc3d9127db637c149162' 
  AND token = 'scB3dUpi2XLzVpIC4jfoNAKmq/oA/9z+Z5F7Woa8fIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}