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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54e6b8a7a5d150bac7fc86ab9888c4a233ad9b086e384c51c4ef4c9d461b0298' 
  AND token = '492epTk7tOfwx/W6b56omxBht3xbqhmHDfJ9c7FcQII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}