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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e78581bac36f9f5e23d7dc05170008b13441619937b6b97a3d8ecdd2834a937' 
  AND token = 'wCFdA5FlZxLNffNsEGF/JkwFDQG8kQ4WBL7p9xsrOAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}