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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '577138765a930ef8d0916f5c7aa421882efc7e1a0a5c242081e98fb6cdeeb748' 
  AND token = 'FiV716suN91OluEa5AE3727L7uXfwWK9jOBUWgk8xGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}