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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd648e709015686dcaf7dbe3c8ed78fac76d9e9e549d49a0b26fa57613791be78' 
  AND token = 'WFsUx7tjLLyzT3ZH9FFuLvAMM5k1a7ftVsQ4MUdCH8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}