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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '880d22aa567d088d93d77585d56e9d257620a32c624f5137d74e20137b4427ee' 
  AND token = '52aU985qH5GJQSZup2r+fHNawag6JjxKGaGzlPNal5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}