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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6b416aa099dec0e40f6e0e2afc84e51eed66d3ec7c1044a4e4e4a3c16533a08' 
  AND token = 'KXC6P6fucRRlQ127/WdePNj4+O9Ddv3II2e75zKhdpY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}