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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c2eaa9d6697b62151a02d2a7879ea07081d6bf68af01f8c957c276b1144cd3b' 
  AND token = '5Xdk4ojs0Z9OqOxy5HwbkfhCyuFtr2K+ShGTvAE4/mc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}